The Designated Emphasis in Translational Research (DETR) is an inter-graduate group program that allows Ph.D. students to receive and be credited for training in the area of translational research. This training is a key component of a larger UCD strategy for creating a groundbreaking translational research program that is team-based and multidisciplinary and to make bold new changes in how we train our basic scientist students to discover answers to medical challenges. The overarching goal of the initiative is to provide an innovative, cost-effective, and sustainable model for training a new cadre of PhD biologists who will have productive careers in clinically-relevant basic research.